Sarafloxacin Hydrochloride (CAS 91296-87-6)
✦ Product Overview
Sarafloxacin Hydrochloride (C₂₀H₁₈ClF₂N₃O₃, MW: 421.83) is a second-generation fluoroquinolone antibiotic with broad-spectrum activity against Gram-negative and Gram-positive bacteria, including E. coli, Salmonella, Streptococcus, and Mycoplasma. As a white to pale yellow crystalline powder, it is hygroscopic and light-sensitive, with high efficacy in veterinary medicine and aquaculture12.
✦ Key Advantages
🔹 High Purity: ≥98% (HPLC-verified), meeting pharmacopeial standards for pharmaceutical use45.
🔹 Potent Antimicrobial Activity: Superior to enrofloxacin, norfloxacin, and amikacin against resistant strains23.
🔹 Thermal Stability: Melting point ≥300°C, stable under recommended storage (2–8°C, sealed)56.
🔹 Water Solubility: ≥0.1 mg/mL in aqueous solutions (pH 3.0–5.0), ideal for formulations56.
✦ Applications
Veterinary Medicine: Treatment of swine Streptococcus suis, poultry E. coli infections, and bovine respiratory diseases.
Aquaculture: Prevention of fish gill rot, enteritis, and bacterial septicemia.
Research: Study of bacterial resistance mechanisms and fluoroquinolone efficacy.
✦ Quality Assurance
Tested via HPLC, FTIR, and mass spectrometry, compliant with USP42, CP, and BP standards. Batch-specific COAs provided, with stability validated per ICH guidelines45.
✦ Market Insights
The global veterinary antibiotics market is projected to grow at 5.1% CAGR (2025–2030), driven by rising demand for livestock health management and aquaculture disease control13.


