Basic information Chemical Properties Clinical evaluation Pharmacological effects Uses Mechanism of action Pharmacokinetics Indications Precautions Production methods Non-depolarizing muscle relaxants Safety Related Supplier

ChemicalBook Product Catalog API Anesthetic Agents Skeletal muscle relaxants Rocuronium bromide

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Rocuronium bromide NEW

$45.00 10mg

$61.00 50mg

$81.00 100mg

Min. Order
Purity99.77%
Cas No119302-91-9
Supply Ability10g
Update time2025-04-29

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

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United States

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Chemical Properties

Product Name	Rocuronium bromide
CAS No	119302-91-9
EC-No
Min. Order
Purity	99.77%
Supply Ability	10g
Release date	2025/04/29

Product Introduction

Bioactivity

Name	Rocuronium bromide
Description	Rocuronium bromide (ORG 9426) is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker. During surgery or mechanical ventilation, it is used to facilitate endotracheal intubation and to provide skeletal muscle relaxation.
In vitro	Rocuronium effectively reduces indirectly elicited twitch tensions in both normal diaphragms (IC50: 9.84 μM) and those pretreated, showing a significant decrease (P < .01, n = 6) in a concentration-dependent manner [1]. It exhibits a similar ED95 for both children and adults, with a duration of action comparable to vecuronium but is shorter in children. Conventional doses of cholinesterase inhibitors can readily reverse its effects [2]. The onset time for maximum block is 1.7 (32) minutes, with the duration until 25% recovery of twitch height at 53 (19) minutes, and recovery from 25% to 75% of twitch height taking 20 (37) minutes [3].
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 113 mg/mL (185.34 mM), Sonication is recommended. H2O : 112 mg/mL (183.7 mM), Sonication is recommended. Ethanol : 113 mg/mL (185.34 mM), Sonication is recommended.
Keywords	Rocuronium Bromide \| Rocuronium bromide \| Rocuronium \| ORG-9426 \| ORG9426 \| mAChR \| Inhibitor \| inhibit
Inhibitors Related	Adiphenine hydrochloride \| Nanofin \| Forskolin \| Pilocarpine Hydrochloride \| Clozapine N-Oxide \| Pilocarpine nitrate \| Urethane \| Ribavirin \| D-Menthol \| Amitriptyline hydrochloride \| Choline chloride \| Propoxur
Related Compound Libraries	FDA-Approved & Pharmacopeia Drug Library \| Failed Clinical Trials Compound Library \| Bioactive Compound Library \| Anti-Neurodegenerative Disease Compound Library \| Approved Drug Library \| Membrane Protein-targeted Compound Library \| Drug Repurposing Compound Library \| Inhibitor Library \| FDA-Approved Drug Library \| Immunology/Inflammation Compound Library \| Clinical Compound Library \| Bioactive Compounds Library Max

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