Product Name：Rebeprazole sodium
CAS Number: 117976-90-6
White to off-white powder with no odor
Product Introduction: Rabeprazole Sodium (CAS#117976-90-6)
Rabeprazole sodium, with the CAS number 117976-90-6, is a highly important pharmaceutical compound that has made significant contributions to the field of medicine, particularly in the treatment of various gastrointestinal disorders.
I. Physical Properties
In its pure form, rabeprazole sodium is a white to off-white crystalline powder. This powder has a fine texture and is highly stable under appropriate storage conditions. The compound is odorless, which is a desirable characteristic for a pharmaceutical ingredient as it reduces the likelihood of unpleasant odors that could potentially cause discomfort to patients.
II. Chemical Properties
Chemically, rabeprazole sodium is a proton pump inhibitor. It works by inhibiting the hydrogen-potassium adenosine triphosphatase (H+/K+-ATPase) enzyme system at the secretory surface of gastric parietal cells. This action reduces the secretion of gastric acid, providing relief from conditions associated with excessive acid production in the stomach.
III. Therapeutic Applications
Rabeprazole sodium is primarily used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger-Ellison syndrome. In GERD, the excessive backflow of stomach acid into the esophagus causes symptoms such as heartburn, regurgitation, and chest pain. Rabeprazole sodium helps to reduce the acidity of the stomach contents, thereby alleviating these symptoms and preventing damage to the esophagus.
For peptic ulcer disease, which includes gastric and duodenal ulcers, rabeprazole sodium promotes healing by reducing the amount of acid that comes into contact with the ulcerated area. This allows the damaged tissue to repair itself more effectively.
In Zollinger-Ellison syndrome, a rare disorder characterized by excessive secretion of gastric acid, rabeprazole sodium is an essential treatment option. It helps to control the high levels of acid production and manage the associated symptoms, such as severe abdominal pain and diarrhea.
IV. Dosage Forms and Administration
Rabeprazole sodium is available in several dosage forms, including tablets, capsules, and injectables. The choice of dosage form depends on the specific needs of the patient and the severity of the condition being treated.
Tablets and capsules are convenient for oral administration and are typically taken once daily. Injectable forms are used in cases where immediate action is required or when oral administration is not possible.
When administered, rabeprazole sodium is rapidly absorbed from the gastrointestinal tract. The onset of action is relatively quick, providing relief to patients within a short period of time. The duration of action is also significant, allowing for long-lasting control of acid secretion.
V. Safety and Side Effects
Like all medications, rabeprazole sodium may cause some side effects. However, the majority of patients tolerate the drug well. Common side effects may include headache, diarrhea, nausea, and abdominal pain. These side effects are usually mild and transient, resolving on their own without the need for specific treatment.
In rare cases, more serious side effects may occur, such as allergic reactions, liver problems, and bone fractures. Patients should be informed about the potential side effects and advised to report any unusual symptoms to their healthcare provider.
Huarong supply the high quality Rabeprazole,For more details ,please contact us.
Eric Huang
Phone:+86 19925801629
Skype:erichjz
Email:eric@huarongpharma.com
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