Product Name: (R)-Phenylephrine Hydrochlorid
Synonyms: (-)-3-[1(R)-Hydroxy-2-(methylamino)ethyl]phenol hydrochloride;Phenylephrine Hydrochloride (200 mg);PHENYLEPHRINE HCL BP ((R)-3-HYDROXY-ALPHA-(METHYLAMINO) METHYL] BENZENEMETHANOLHYDROCHL ORIDE);(-)-3-HYDROXY-ALPHA-(METHYLAMINOMETHYL)BENZYL ALCOHOL HYDROCHLORIDE;L-1-(M-HYDROXYPHENYL)-2-METHYLAMINOETHANOL HYDROCHLORIDE;L-(3-HYDROXYPHENYL)-N-METHYLETHANOLAMINEHYDROCHLORIDE;L-A-HYDROXY-B-METHYLAMINO-3-HYDROXY-1-ETHYLBENZENE HYDROCHLORIDE;L(-)-PHENYLEPHRINE HCL
CAS: 61-76-7
MF: C9H13NO2.ClH
MW: 203.67
EINECS: 200-517-3
Product Categories: Adrenergic Agents;AFRIN;Amines;Aromatics;Chiral Reagents;API;Intermediates & Fine Chemicals;Pharmaceuticals;pharmaceutical raw material;Pharmaceutical intermediates;61-76-7
R-(-)-Phenylephrine is an adrenergic α1A receptor agonist (Ki = 1.4 μM) that demonstrates selectivity against the α1B and α1C receptor subtypes (Kis = 23.9 and 47.8 μM, respectively). By stimulating adrenergic α1 receptors, L-phenylephrine can induce aortic smooth muscle contractions, although reported relative affinity and potency values in rabbit are 5-fold weaker compared to that of L-norepinephrine . This compound is frequently used to precontract smooth muscle in preparations designed to study the properties of various vasodilator agents.
China
