1. Materials information
Names
| Name | Oleuropein |
|---|
| Synonym | More Synonyms |
|---|
Oleuropein Biological Activity
| Description | Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity[1]. Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits aromatase[2]. |
|---|
| Related Catalog | Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Cardiovascular Disease Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Research Areas >> Inflammation/Immunology Signaling Pathways >> Others >> Aromatase |
|---|
| Target | PPARγ Apoptosis Aromatase |
|---|
| In Vitro | Aromatase, a cytochrome P450 enzyme, is an important pharmacological target in breast cancer therapy[2]. |
|---|
| References | [1]. Svobodova M, et al. Oleuropein as an inhibitor of peroxisome proliferator-activated receptor gamma. Genes Nutr. 2014 Jan;9(1):376. [2]. Gorzynik-Debicka M, et al. Potential Health Benefits of Olive Oil and Plant Polyphenols. Int J Mol Sci. 2018 Feb 28;19(3). pii: E686. |
|---|
Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
|---|
| Boiling Point | 772.9±60.0 °C at 760 mmHg |
|---|
| Melting Point | 89-90ºC |
|---|
| Molecular Formula | C25H32O13 |
|---|
| Molecular Weight | 540.514 |
|---|
| Flash Point | 257.0±26.4 °C |
|---|
| Exact Mass | 540.184265 |
|---|
| PSA | 201.67000 |
|---|
| LogP | -0.91 |
|---|
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
|---|
| Index of Refraction | 1.630 |
|---|
| Storage condition | room temp |
|---|
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|
| Hazard Codes | Xn |
|---|
| Safety Phrases | 24/25 |
|---|
| RIDADR | NONH for all modes of transport |
|---|
| HS Code | 2938909090 |
|---|
2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
For more details, pls contact us freely.
Email address: Tina@fdachem.com
Mob: 86 15225627621
WhatsApp/Skype/Wechat/LINE: 86 15225627621
China
CAS#:10597-60-1
CAS#:178600-68-5
