Name | Oleuropein |
Description | Oleuropein is an antioxidant polyphenol isolated from olive leaf. |
In vitro | In both J774A.1 cells and primary mouse macrophages, Oleuropein increases LPS-induced NO production. [1] Oleuropein prevents oxidative myocardial injury induced by ischemia and reperfusion. [2] In TF-1a; 786-O, T-47D, RPMI-7951, LoVo, and NL-Fib cells, Oleuropein inhibits cell proliferation and migration. [3] |
In vivo | In swiss albino mice that spontaneously develop soft tissue sarcomas, Oleuropein (i.p. or p.o.) completely regresses tumors. [3] In rats, Oleuropein (40 mg/kg, p.o.) protects from cardiac remodeling process after isoproterenol-induced myocardial infarction through inhibiting angiotensin-converting enzyme activity. [4] |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 50 mg/mL (92.51 mM) H2O : 92 mg/mL (170.2 mM) Ethanol : 93 mg/mL (172.1 mM)
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Keywords | PPARγ | olive | PPAR | Peroxisome proliferator-activated receptors | inhibit | Apoptosis | leaves | Aromatase | oil | Oleuropein | anti-atherogenic | cancer | antioxidant | breast | Inhibitor | anti-inflammatory |
Inhibitors Related | Stavudine | TBHQ | 5-Fluorouracil | Meclizine dihydrochloride | Dextran sulfate sodium salt (MW 4500-5500) | Sodium 4-phenylbutyrate | Sorafenib | Tributyrin | Lidocaine hydrochloride | 2,3-Butanediol | Alginic acid | Oleic acid |
Related Compound Libraries | Anti-Tumor Natural Product Library | Terpene Natural Product Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Flavor Compound Library | Natural Product Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library for HTS | Cosmetic Ingredient Compound Library | Anti-Cancer Active Compound Library |