Chinese name: N-methylpyrrolidone
English name: N-Methyl-2-pyrrolidone
CAS: 872-50-4
EINECS number: 212-828-1
Molecular formula: C5H9NO
MDL number: MFCD00003193
Molecular weight: 99.13
Appearance: Colorless transparent oily liquid, slightly amine odor. It can be miscible with water, alcohol, ether, ester, ketone, halogenated hydrocarbon and aromatic hydrocarbon.
Solubility: It can be miscible with water, alcohol, ether, ester, ketone, halogenated hydrocarbon and aromatic hydrocarbon.
Melting point: −24 °C(lit.)
Boiling point: 202 °C(lit.)
Density: 1.028 g/mL at 25 °C(lit.)
Vapor density: 3.4 (vs air)
Vapor pressure: 0.29 mm Hg (20 °C)
Refractive index: n20/D 1.479
Flash point: 187 °F
Storage conditions: 2-8°C
Solubility: miscible ethanol, solubility is 0.1ML/mL, transparent, colorless (10%,v/v)
Predicted Acidity coefficient (pKa) : -0.41±0.20
Form: Liquid
Color: ≤20(APHA)
PH value: 8.5-10.0 (100g/l, H2O, 20℃)
Odor: Slightly amine odor
Acid-base indicator color change ph range: 7.7-8.0
Water solubility: >=10 g/100 mL at 20 ºC
Sensitivity: hygroscopicity
Maximum wavelength (λmax) : 283nm(MeOH)(lit.)
Merck: 14,6117
InChIKey: SECXISVLQFMRJM-UHFFFAOYSA-N
LogP: -0.46 at 25℃
use
It is an excellent solvent, widely used as an extraction agent for aromatics extraction, lubricating oil refining, acetylene concentration, syngas desulfurization, etc., and also used in industrial cleaning
Preparation method
It is produced by the reaction of gamma-butyrolactone with methylamine. The first step is the reaction of gamma-butyrolactone and methylamine to form 4-hydroxy-n-methylbutyamide, and the second step is further dehydration to form N-methylpyrrolidone. The two-step reaction can be carried out continuously in a tubular reactor with a molar ratio of γ-butyrolactone to methylamine of 1:1.15, a pressure of about 6MPa and a temperature of 250℃. After the reaction is complete, the finished product is concentrated and distilled under pressure. The yield is 90%. If the reactor is used for production, the amount of methylamine is 1.5-2.5 times the theoretical amount, taking laboratory preparation as an example. Add 2mol gamma-butyrolactone and 4 moles of liquid methylamine into a 500ml autoclast, heat tightly, and keep at 280℃ for 4h. After cooling, excessive methylamine is released, distilled, and the fraction of 201-202℃ is collected to obtain about 180g of product with a yield of about 90%. Raw material consumption (kg/g) gamma-butyrolactone 980 methylamine (40%) 860
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