Name | N-Nitrosodiethylamine |
Description | N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine primarily found in water, tobacco smoke, cheddar cheese, cured and fried meals, and many alcoholic beverages. NDEA is responsible for changes in nuclear enzymes related to DNA repair/replication and induces various tumors in all animal species, targeting mainly the liver, nasal cavity, trachea, lung, and esophagus. |
In vivo | Mice with N-Nitrosodiethylamine (25mg/kg) intraperitonially resulted in fatty liver disease leading to progress of cancer disease. |
Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | H2O : 98 mg/mL (959.47 mM), Sonication is recommended. DMSO : 50 mg/mL (489.52 mM), Sonication is recommended.
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Keywords | Inhibitor | N Nitrosodiethylamine | DNA/RNA Synthesis | inhibit | NNitrosodiethylamine | N-Nitrosodiethylamine |
Inhibitors Related | Rifampicin | 5-Fluorouracil | Ribavirin | Guanidine hydrochloride | 2,4-D | Resveratrol | Acyclovir | Thymidine | Temozolomide | Folic acid |
Related Compound Libraries | Anti-Tumor Natural Product Library | DNA Damage & Repair Compound Library | Bioactive Compound Library | Natural Product Library | Tobacco Monomer Library | Natural Product Library for HTS | RO5 Drug-like Natural Product Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |