Synonyms:
methylene blue hydrate, pure | cino 52015 | phenothiazin-5-ium,3,7-bis(dimethylamino)-, chloride, hydrate (9ci) | methylene blue hydrate | methylene blue extra pure | ci 52015 | methylene blue, high purity | methylenebluehydrat | phenothiazin-5-ium,3,7-bis(dimethylamino)-, chloride, hydrate (1:1:?) | c.i. 52015 hydrate | basic blue 9~c.i. 52015 | methylene blue for microscopy
Biological Activity for Methylene Blue
Methylene Blue is a biological stain and redox indicator. Methylene blue inhibits monoamine oxidase A, tau filament formation and nitric oxide synthase (IC50 values = 0.07 μM, 1.9 μM and 5.3 μM, respectively), and inhibits guanylate cyclase. Methylene Blue delays senescence and stimulates proliferation of fibroblasts and skin cells. Methylene Blue promotes wound healing, upregulates elastin expression and production in vitro, increases synthesis of heme, is neuroprotective (EC50 = 0.18 nM) and rescues the loss of dopaminergic neurons induced by Rotenone (Cat. No. 3616). Also antimalarial.
Technical Data for Methylene Blue
| M. Wt | 319.85 |
| Formula | C16H18ClN3S |
| Storage | Store at RT |
| CAS Number | 61-73-4 |
| PubChem ID | 6099 |
| InChI Key | CXKWCBBOMKCUKX-UHFFFAOYSA-M |
| Smiles | CN(C)C1=CC=C2C(SC(C3=N2)=C/C(C=C3)=[N+](C)/C)=C1.[Cl-]
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