1. Materials informatio
Names
| Name | methyl salicylate |
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| Synonym | More Synonyms |
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Methyl salicylate Biological Activity
| Description | Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent. Also used as a pesticide, a denaturant, a fragrance ingredient, and a flavoring agent in food and tobacco products[1]. A systemic acquired resistance (SAR) signal in tobacco[2]. A topical nonsteroidal anti-inflammatory drug (NSAID). Methyl salicylate lactoside is a COX inhibitor[4]. |
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| Related Catalog | Signaling Pathways >> Immunology/Inflammation >> COX Natural Products >> Acids and Aldehydes Research Areas >> Inflammation/Immunology |
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| In Vitro | Methyl Salicylate is a systemic acquired resistance signal in tobacco. It (0-1 mg/L) esterases activity of salicylic acid–binding protein 2 (SABP2), which converts MeSA into salicylic acid (SA), is required for SAR signal perception in systemic tissue[2]. |
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| References | [1]. Greene T, et al. A critical review of the literature to conduct a toxicity assessment for oral exposure to methyl salicylate. Crit Rev Toxicol. 2017 Feb;47(2):98-120. [2]. Park SW, et al. Methyl salicylate is a critical mobile signal for plant systemic acquired resistance. Science. 2007 Oct 5;318(5847):113-6. [3]. Lapczynski A, et al. Fragrance material review on methyl salicylate. Food Chem Toxicol. 2007;45 Suppl 1:S428-52. [4]. Xin W, et al. Methyl salicylate lactoside inhibits inflammatory response of fibroblast-like synoviocytes and joint destruction in collagen-induced arthritis in mice. Br J Pharmacol. 2014 Jul;171(14):3526-38. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 222.0±0.0 °C at 760 mmHg |
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| Melting Point | -8 °C |
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| Molecular Formula | C8H8O3 |
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| Molecular Weight | 152.147 |
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| Flash Point | 86.8±12.6 °C |
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| Exact Mass | 152.047348 |
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| PSA | 46.53000 |
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| LogP | 2.23 |
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| Vapour density | 5.26 (vs air) |
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| Vapour Pressure | 0.1±0.4 mmHg at 25°C |
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| Index of Refraction | 1.547 |
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| Stability | Stable. Incompatible with strong oxidizing agents, strong bases. |
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| Water Solubility | 0.07 g/100 mL (20 ºC) |
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2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
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