| Mepivacaine hydrochloride Basic information |
| Product Name: | Mepivacaine hydrochloride |
| Synonyms: | Mepivacaine Hydrochloride (200 mg);Ropivacaine base Mepivacaine HCL;(1-methyl-dl-piperidine-2-carboxylicacid)-2,6-dimethylanilidehydrochloride;1-methyl-2’,6’-pipecoloxylididehydrochloride;Mepivacaine HCl USP;2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride;2',6'-Pipecoloxylidide, 1-methyl-, monohydrochloride (6CI, 8CI);2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride (9CI) |
| CAS: | 1722-62-9 |
| MF: | C15H22N2O.ClH |
| MW: | 282.81 |
| EINECS: | 217-023-9 |
| Product Categories: | API;Sodium channel;Amines;Aromatics;Heterocycles;Analgesic series;Intermediates & Fine Chemicals;Pharmaceuticals;1722-62-9 |
| Mol File: | 1722-62-9.mol |
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| Mepivacaine hydrochloride Chemical Properties |
| Melting point | 255-257°C (dec.) |
| storage temp. | 2-8°C |
| solubility | H2O: soluble20mg/mL, clear |
| form | powder |
| color | white to beige |
| InChI | InChI=1S/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H |
| InChIKey | RETIMRUQNCDCQB-UHFFFAOYSA-N |
| SMILES | C1(=C(C)C=CC=C1C)NC(=O)C1CCCCN1C.Cl |
| CAS DataBase Reference | 1722-62-9(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride (1722-62-9) |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 22-24/25 |
| RIDADR | UN 2811 6.1 / PGIII |
| RTECS | TK6475000 |
| HS Code | 29333990 |
| Toxicity | LD50 in mice, rats (mg/kg): 280, 500 s.c. (Aberg) |
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| Mepivacaine hydrochloride Usage And Synthesis |
| Chemical Properties | White Solid |
| Uses | anesthetic (local) |
| Uses | Mepivacaine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography. |
| Uses | An anti-inflammatory and analgesic |
| Definition | ChEBI: The hydrochloride salt of mepivacaine. It is used as a local anaesthetic. |
| Brand name | Arestocaine Hydrochloride (Solvay Pharmaceuticals); Carbocaine (Hospira); Isocaine Hydrochloride(Novocol); Polocaine (AstraZeneca); Polocaine (Dentsply); Scandonest (Deproco). |
| Biological Functions | Mepivacaine hydrochloride (Carbocaine) is longer acting than lidocaine and has a more rapid onset of action (3–5 minutes). Topical application is not effective. It has been widely used in obstetrics, but its use has declined recently because of the early transient neurobehavioral effects it produces. Adverse reactions associated with mepivacaine are generally similar to those produced by other local anesthetics. It can be used with epinephrine or levonordefrin (dental use only). |
| General Description | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Mepivacaine hydrochloride is a local anesthetic that is related chemically and pharmacologically to the amide-type local anesthetics. It is often administered via local infiltration, peripheral nerve block, etc. |
| Biochem/physiol Actions | Local anesthetic. Reversibly blocks transient Na+ inward current, as well as the steady-state K+ outward current. Blocks tandem pore (TASK) and Kv1.5, potassium channels in model systems. |
| Safety Profile | skin irritant. Questionable carcinogen with |
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| Mepivacaine hydrochloride Preparation Products And Raw materials |
| Preparation Products | 2-[[(2,6-Di(Methyl-d3)phenyl)aMino]carbonyl]-1,1-diMethyl-piperidiniuM Iodide |
Product picture
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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