Lactulose can not be assimilate in the small intestine, and only reach the large intestine can it be used by bifidobacteria and heighten the proliferative activity of it. Therefore lactulose is classified as low calorific sweetener and food additives. In addition to that, it used in medicine for the treatment of constipation and the venous system disease.
Lactulose is a synthetic, non-digestible sugar used in the treatment of chronic constipation and hepatic encephalopathy, a complication of liver disease. It is a disaccharide (double-sugar) formed from one molecule each of the simple sugars (monosaccharides) fructose and galactose. Lactulose is not normally present in raw milk, but is a product due to the heat-processes: the more the heat, the more the presence of this substance (from 3.5 mg/l in low temperature pastorized milk to 744 mg/l in in-container sterilized milk).It is produced commercially by isomerization of lactose.
It is broadly classified as an osmotic laxative. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
| English Name: | Lactulose |
| English synonyms: | 4-O-BETA-D-GALACTOPYRANOSYL-D-FRUCTOFURANOSE;4-O-BETA-D-GALACTOPYRANOSYL-D-FRUCTOSE;LACTULOSE;4-O-β-D-Galactopyranosyl-D-fructofuranose;LACTULOSE CRYSTALLINE;LACTULOSE ABOUT 98%;LACTULOSE, >95%;Lactulose, 50 wt.% solution in water |
| CAS: | 4618-18-2 |
| Molecular formula: | C12H22O11 |
| Molecular weight: | 342.3 |
| EINECS: | 225-027-7 |
| Melting point | ~169 °C (dec.) |
| Specific rotation | -47 º (C=5, H2O, 12HR) |
| Boiling point | 397.76°C (rough estimate) |
| Density | 1,32g/cm |
| Refractive index | 1,45-1,47 |
| Storage conditions | Refrigerator |
| Solubility | Freely soluble in water, sparingly soluble in methanol, practically insoluble in toluene. |
| Form | Powder |
| Colour | White to almost white |
| Optical activity | [α]20/D 48±2°, 24 hr, c = 1% in H2O |
| Water solubility | 76.4 G/100 ML (30 ºC) |
| Application | Isomerized lactose is not absorbed by human body, but it can promote the proliferation of intestinal bifidobacteria and is beneficial to health.. |
| Purpose | It has the function of reducing blood ammonia and reducing diarrhea. It is mainly used to treat ammonia hepatic coma, hyperammonia and habitual constipation. |
Function:
1.Lactulose for the treatment of constipation
2.Can promote the proliferation of intestinal bifidobacteria, is conducive to good health.
3.Reduces blood ammonia and laxative effects, and is mainly used to treat ammonia-induce
4.hepatic coma, hyperammonemia, and habitual constipation.
5.Scientific research and experimentation. Industrially used as an indirect nutritional supplement.
Application
1. Lactulose is used in the treatment of chronic constipation in patients of all ages as a long-term treatment.
2. Lactulose is useful in treating hyperammonemia
3. It is generally regarded as safe during breastfeeding
Hebei Jingbo New Material Technology Co., Ltd. was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector among Beijing Tianjin and Hebei and has advantage of convenient transportation . Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.Our company has strong technical strength, advanced equipment, strict quality management system and high-quality after-sales service, adhers to the "customer first and forge ahead" business philosophy and insists on integrity as the company's survival.
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