1. Lactulose is an artificially synthesized non absorbable disaccharide that is not absorbed in the intestine. It can be broken down by colon bacteria into lactic acid and acetic acid, causing the pH value of the intestine to fall below 6. This can block the absorption of ammonia, reduce the accumulation and absorption of endotoxins, and restore the patient's blood ammonia to normal, turning from coma to consciousness.
2. Lactulose also has the osmotic activity of disaccharides, which can retain water and electrolytes in the intestinal cavity and produce a hypertonic effect. Therefore, it is also a permeable laxative and can be used to treat chronic functional constipation because it has no intestinal irritation.
3. It has an anti endotoxin effect.