Technical Data Sheet (TDS)
Icariin (≥98% by HPLC, Food & Industrial Grade)
1. Product Identification
Product Name: Icariin
Synonyms: Epimedium extract; Horny Goat Weed Extract; Icariine
Chemical Name: 5-Hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-(3-methylbut-2-enyl)chromen-4-one
Molecular Formula: C₃₃H₄₀O₁₅
Molecular Weight: 676.65
CAS No.: 489-32-7
EINECS No.: 207-793-1
2. Description
Icariin is a natural flavonoid glycoside extracted primarily from Epimedium brevicornum Maxim (Horny Goat Weed). It is known for its pharmacological properties such as enhancing vitality, supporting sexual health, improving cardiovascular function, and acting as an antioxidant.
In industrial use, it is valued as a bioactive compound in nutraceuticals, pharmaceuticals, and cosmetic formulations.
3. Physical & Chemical Properties
| Item | Specification | Typical Result |
|---|
| Appearance | Yellow to light brown powder | Yellow fine powder |
| Odor & Taste | Characteristic, slightly bitter | Characteristic |
| Solubility | Slightly soluble in ethanol, practically insoluble in water | Conforms |
| Assay (Icariin by HPLC) | ≥98% | 98.5% |
| Melting Point | 231–233°C | 232°C |
| Loss on Drying | ≤5.0% | 3.2% |
| Ash | ≤2.0% | 1.5% |
| Heavy Metals | ≤10 ppm | 6 ppm |
| Lead (Pb) | ≤2 ppm | 1.2 ppm |
| Arsenic (As) | ≤1 ppm | 0.3 ppm |
| Cadmium (Cd) | ≤1 ppm | 0.1 ppm |
| Mercury (Hg) | ≤0.1 ppm | <0.05 ppm |
| Total Plate Count | ≤1000 CFU/g | 250 CFU/g |
| Yeast & Mold | ≤100 CFU/g | 20 CFU/g |
| E. coli | Negative | Negative |
| Salmonella | Negative | Negative |
4. Applications
Food & Nutraceutical Use:
Ingredient in dietary supplements promoting vitality, endurance, and hormone balance
Used in male enhancement and energy support formulations
Functional food additive for antioxidant and anti-aging benefits
Industrial & Pharmaceutical Use:
Active ingredient in herbal medicine and health products
Used in formulations for improving blood circulation and bone health
Functional compound in cosmetics for anti-aging and antioxidant effects
5. Handling and Storage
Storage Conditions: Store in a tightly sealed container, in a cool (below 25°C), dry, and well-ventilated area.
Avoid: Heat, moisture, and direct sunlight.
Shelf Life: 3 years under proper storage conditions.
Packaging: 25 kg/drum, inner double PE bags.
6. Safety Information
Hazard Identification: Non-toxic in normal handling; avoid inhalation of dust.
Handling Precautions: Use personal protective equipment (gloves, mask, goggles).
First Aid Measures:
Inhalation: Move to fresh air.
Skin Contact: Wash with soap and water.
Eye Contact: Rinse thoroughly with water.
Ingestion: Rinse mouth, seek medical advice if necessary.
7. Regulatory Information
Complies with EU Regulation (EC) No. 1881/2006 for contaminants in foodstuffs.
Meets USP/EP analytical testing standards.
Non-GMO, Non-Irradiated, and free from residual solvents (per ICH Q3C).
8. Disclaimer
The information contained in this document is believed to be accurate and reliable. However, the user is responsible for determining the suitability of this product for specific applications and compliance with local regulations.
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