Ethidium bromide NEW

• MOLECULAR FORMULA :

• C21-H20-N3.Br

• MOLECULAR WEIGHT :

• 394.35

• WISWESSER LINE NOTATION :

• T B666 HKJ EJ H2 IR& LZ &E &9/26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

• TYPE OF TEST :

• LDLo - Lowest published lethal dose

• ROUTE OF EXPOSURE :

• Intraperitoneal

• SPECIES OBSERVED :

• Rodent - mouse

• DOSE/DURATION :

• 20 mg/kg

• TOXIC EFFECTS :

• Tumorigenic - active as anti-cancer agent

• TYPE OF TEST :

• LD50 - Lethal dose, 50 percent kill

• ROUTE OF EXPOSURE :

• Subcutaneous

• SPECIES OBSERVED :

• Rodent - mouse

• DOSE/DURATION :

• 110 mg/kg

• TOXIC EFFECTS :

• Details of toxic effects not reported other than lethal dose value

• TYPE OF TEST :

• Sex chromosome loss and nondisjunction

• TYPE OF TEST :

• Specific locus test

• TYPE OF TEST :

• Dominant lethal test

• TYPE OF TEST :

• Micronucleus test

• TYPE OF TEST :

• DNA inhibition

• TYPE OF TEST :

• Sister chromatid exchange

MUTATION DATA

• TEST SYSTEM :

• Bird - chicken

• DOSE/DURATION :

• 847 ug/kg

• REFERENCE :

• 47JMAE "Cytogenetic Assays of Environmental Mutagens," Hsu, T.C., ed., Totowa, NJ, Allanheld, Osmun & Co., 1982 Volume(issue)/page/year: -,137,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1168 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 34 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1168 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 21 (estimated)