Product Name: Doxycycline hydrochloride
CAS: 10592-13-9
MF: C22H25ClN2O8
MW: 480.9
EINECS: 234-198-7
Melting point 195-201ºC
Fp 87ºC
storage temp. Inert atmosphere,2-8°C
solubility H2O: 50 mg/mL, clear, yellow-green
form powder
color yellow
Water Solubility Soluble in water.
| Item | Index | Result |
| Description | Yellow crystalline powder | Conform |
| Assay | 95%-100% | 99% |
| Identification | a) TLC testformed | Conform |
| b) Color reaction with sulfuric acid | Conform |
| c) Chloride reaction with silver nitrate | Conform |
| Ph | 2.3-2.9 | 2.5 |
| Specific optical rotation | Between -188° and -200° | -193º |
| Absorbance: (353nm,E1%, 1cm) | Between 270 and 290 | 276 |
| Light absorbing impurity: | a) The absorbance at 430nm should not be greater than 0.50 | Conform |
| b) The absorbance at 490nm should not be greater than 0.20 | Conform |
| Related substances: | a) 4-epioxytetracycline≤0.5% | Conform |
| b) Tetracycline:≤2.0% | Conform |
| c) Total mixture of α,ß-apo-oxytetracycline ≤2.0% | Conform |
| d) Peak on the tail of the main peak:2.0% | Conform |
| Heavy metals | Not more than 50ppm | Conform |
| Suphated ash | Not more than 0.5% | 0.01% |
| Water | Not more than 2.0% | 0.86% |
| Endotoxin | Not more than 0.4I.E./mg | Conform |
Application
1. Doxycycline hydrochloride is a salt prepared from doxycycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in hydrochloric aci d solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, doxycycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis.
2. Doxycycline hydrochloride, is used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and to eliminate Ixodes scapularis ticks. It is a broad spectrum inhibitor used to inhibit matrix metalloproteinases (MMP), such as type 1 collagenase in studies on wound healing and tissue remodeling.
Company Profile
Hebei Zhuanglai Chemical Trading Co.,Ltd. is a foreign trading company, specializing in developing and producing Chemical raw materials, pharmaceutical intermediates.It has its own factory, which procures itself a competitive edge in market.
For many years, our company has won many clients' support and trust because it always strives to make high-quality merchandise with favorable price. It commits itself to satisfy every clients, in return, our customer show great confidence and respect for our company. In spite of so many loyal customers won these years, Hegui keeps modest all the time and strives to better itself from every aspect.
We are looking forward to cooperating with you and having a win-win relationship with you. Please rest assured that we will satisfy you. Just feel free to contact me.
Packing & Shipping
FAQ
Q1. What is your delivery term and delivery period?
We accept FOB, CIF, etc. You can choose the one which is the most convenient or cost effective for you. Competitive price with ready stocks; by Air within 7days, by sea within 14 days shipping after .
Q2. What's your main markets?
South&North America, Europe, Asia, Africa etc. Top customers among more than 80 countries; 30 years history; One-stop supplier.
Q3. What is the payment term?
Normally we advise customers use Trade Assurance(is a free payment protection service for buyers is offered by Alibaba group), and we also receive T/T, Western Union or L/C.
Q4. Will you supply samples for test the quality?
We'd like to offer our customers samples for the quality evaluation for most products to develop business.
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