Manufacturer Provide Veterinary Raw Material Diaveridine CAS 5355-16-8 Diaveridine HCl
Introduction
1.Product Name:Diaveridine
2.Synonym:DIAVERIDIN
3.CAS NO: 5355-16-8
4.Purity: 99%min
5.Appearance:Almost White or Yellowish Crystalline Powder
6.Molecular formula: C13H16N4O2
7.Molecular weight :260.29
8.Melting Point :233 °C(lit.)
9.Storage Temperature :Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
10.Packing: Bag, drum
Diaveridine is a dihydrofolate reductase (DHFR) inhibitor with a Ki of 11.5 nM for the wild type DHFR and also an antibacterial agent. Treatments with Diaveridine for 90 min have a strong bactericidal effect on S. typhimurium TA1535, and no bacterial growth is observed at 10μg/mL or more. Without metabolic activation, treatment with Diaveridine for 48 h, but not 24 h, causes a dose-dependent, significant increase in the frequency of aberrant metaphases. At 100 μg/mL, 60% of the metaphases contain chromosome aberrations.
| Index | Standard | Test result |
| Appearance | Almost white or yellowish crystalline powder | Conforms |
| Clarity of solution | Clear | Conforms |
| Color of solution | Not more intensely coloured than BY4 |
|
| Acidity | PH=3.5~6.0 | PH 3.8 |
| Loss on drying | ≤3.0% | 0.38% |
| Solubility | ≥2.0% | >2.0%(70°C) |
| Assay | ≥98.0%(The dried sunstance) | 100.2%(The dried sunstance) |
China
