What is Diaveridine?
Diaveridine is a dihydrofolate reductase (DHFR) inhibitor with a Ki of 11.5 nM for the wild type DHFR and also an antibacterial agent. Treatments with Diaveridine for 90 min have a strong bactericidal effect on S. typhimurium TA1535, and no bacterial growth is observed at 10μg/mL or more. Without metabolic activation, treatment with Diaveridine for 48 h, but not 24 h, causes a dose-dependent, significant increase in the frequency of aberrant metaphases. At 100 μg/mL, 60% of the metaphases contain chromosome aberrations. .
Function of Diaverdine
Diaveridine has antibacterial effect, to sulfa drugs and antibiotics is an obvious synergistic effect, internal and absorb less, high concentration within the gastrointestinal, so it is suitable for intestinal infection, the product of sulfanilamide or sulfanilamide blend of armour pyrimidine premix can be added in the feed, can also be tablet paste, respectively to the rabbit, opening to the outside world coccidiosis and livestock and poultry intestinal infection has good control effect. .
Application of Diaveridine
Veterinary medicine sulfonamide synergist for bacterial infection prevention and control of poultry.Diaveridine is also a coccidoistat, share, and evil ketoneses sulfonamide moiety in the treatment of poultry coccidiosis..
Hebei Jingbo New Material Technology Co., Ltd. was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector among Beijing Tianjin and Hebei and has advantage of convenient transportation . Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.Our company has strong technical strength, advanced equipment, strict quality management system and high-quality after-sales service, adhers to the "customer first and forge ahead" business philosophy and insists on integrity as the company's survival.
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