| Name | Desogestrel |
| Description | Desogestrel (Cerazette) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents. |
| In vivo | Desogestrel is extensively metabolized after oral administration to rats and dogs; In rats, desogestrel is metabolized mainly at the C3, C5, C11, and C15 positions. An hydroxy group is introduced at the 15α-position of desogestrel, followed by conjugation with glucuronic acid. In dogs, desogestrel is mainly metabolized at the C3- and C17-positions[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (3.22 mM), Sonication is recommended. Ethanol : 58 mg/mL (186.81 mM), Sonication is recommended. DMSO : 58 mg/mL (186.81 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble or slightly soluble)
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| Keywords | progestogenReceptor | progestogen Receptor | ProgesteroneReceptor | Progesterone Receptor | PR | Org2969 | Org 2969 | NR3C3 | Inhibitor | inhibit | EstrogenReceptor | Estrogen Receptor | ER | Desogestrel |
| Inhibitors Related | Tamoxifen | Mifepristone | Estradiol | Astragaloside IV | Estradiol benzoate | Bisphenol Z | 17α-Hydroxyprogesterone | Ethisterone | Alpha-Estradiol | Ferrous Bisglycinate | Megestrol acetate | Hinokitiol |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Failed Clinical Trials Compound Library | Bioactive Compound Library | Pediatric Drug Library | ReFRAME Related Library | Drug Repurposing Compound Library | Endocrinology-Hormone Compound Library | FDA-Approved Drug Library | Bitter Compound library | Bioactive Compounds Library Max | Bioactive Lipid Compound Library | Human Metabolite Library |