Name	Clorsulon
Description	Clorsulon (L631529) is utilized for the treatment of Fasciola hepatica infections in calves and sheep.
In vitro	In sheep and calves, a single administration of Clorsulon (15 mg/kg) effectively induces damage to the cortical and intestinal tissues of the liver flukes, thereby expelling immature liver flukes from the host organism.
In vivo	Clorsulon is a competitive inhibitor (Ki=0.29 mM) of both 3-phosphoglycerate and ATP, capable of suppressing glucose utilization and the formation of acetate and propionate.
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	Ethanol : 7 mg/mL (18.38 mM) H2O : < 1 mg/mL (insoluble or slightly soluble) DMSO : 71 mg/mL (186.5 mM)
Keywords	Fasciola \| 3-phosphoglycorate \| Inhibitor \| glucose utilization \| L 631529 \| gigantica \| Clorsulon \| Parasite \| L-631529 \| MK 401 \| MK-401 \| inhibit \| Flukicidal
Inhibitors Related	Neomycin sulfate \| Ampicillin sodium \| Kanamycin sulfate \| Sulfamethoxazole sodium \| Hydroxychloroquine \| Metronidazole \| Doxycycline \| EDTA copper(II) disodium salt
Related Compound Libraries	FDA-Approved & Pharmacopeia Drug Library \| Anti-Parasitic Compound Library \| Bioactive Compound Library \| Membrane Protein-targeted Compound Library \| Inhibitor Library \| NO PAINS Compound Library \| Mitochondria-Targeted Compound Library \| Bioactive Compounds Library Max \| Ion Channel Targeted Library \| Human Metabolite Library

Clorsulon NEW

Product Introduction