Product Name: Clorsulon
Synonyms: keluosuolong;4-amino-6-(trichloroethenyl)-3-benzenedisulfonamide;curatrem;l631529;4-AMINO-6-(TRICHLORO-ETHENYL)-1,3-BENZENEDISULFONAMIDE;4-AMINO-6-TRICHLOROVINYL-1,3-BENZENEDISULFONAMIDE;4-AMINO-6-(TRICHLOROVINYL)-M-BENZENEDISULFONAMIDE;CLORSULON
CAS: 60200-06-8
MF: C8H8Cl3N3O4S2
MW: 380.66
EINECS: 262-100-2
Product Categories: -;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;ZOMAX
Mol File: 60200-06-8.mol
Clorsulon Structure
Clorsulon Chemical Properties
Melting point 194-203°C
Boiling point 651.7±65.0 °C(Predicted)
density 1.800±0.06 g/cm3(Predicted)
storage temp. 0-6°C
pka 9.16±0.60(Predicted)
form neat
CAS DataBase Reference 60200-06-8(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 2
RTECS CZ9090000
HS Code 29350090
Toxicity LD50 in mice (mg/kg): 761 i.p.; >10,000 orally (Ostlind)
MSDS Information
Clorsulon Usage And Synthesis
Chemical Properties Crystalline Solid
Uses analgesic, antiinflammatory
Uses A benzenedisulfonamide derivative with fasciolicidal activity. Anthelmintic (Trematodes)
Brand name Curatrem [Veterinary] (Merial).
Veterinary Drugs and Treatments Clorsulon is approved for use in the treatment of immature and adult forms of Fasciola hepatica (Liver fluke) in cattle. It is not effective against immature flukes less than 8 weeks old. It also has activity against Fasciola gigantica. Although not approved, the drug has been used in practice in various other species (e.g., sheep, llamas). It has activity against F. magna in sheep, but is not completely effective in eradicating the organism after a single dose, thus severely limiting its clinical usefulness against this parasite. Clorsulon is also not effective against the rumen fluke (Paramphistomum).
China
