| Name | Choline chloride |
| Description | Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. |
| In vitro | After oral administration of Choline chloride, clinical symptoms include restlessness, accelerated respiration, reduced activity, convulsions, wrinkled fur, unsteady gait, and respiratory distress. Choline chloride exhibits low acute oral toxicity. Some animals exhibit diarrhea following ingestion of Choline chloride. In one study, the autopsy revealed pulmonary inflammation in 30% of the rats in the high-dose group. |
| In vivo | In cell culture, a deficiency of choline can lead to apoptosis, also known as programmed cell death. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 27 mg/mL (193.37 mM), Sonication is recommended.
H2O : 26 mg/mL (186.21 mM), Sonication is recommended.
DMSO : 50 mg/mL (358.09 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (23.63 mM), Sonication is recommended.
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| Keywords | Nicotinic acetylcholine receptors | nAChR | mAChR | Inhibitor | inhibit | Endogenous Metabolite | Choline chloride | Choline Chloride | Choline | anti-inflammatory | analgesic | alpha7 nicotinic receptor |
| Inhibitors Related | Sucrose | Aceglutamide | Emtricitabine | 3-Hydroxybutyric acid sodium | Levulinic acid | D(+)-Raffinose pentahydrate | D-(+)-Trehalose dihydrate | Glycerol | Thymidine | Sodium 2-hydroxybutanoate | Chitosan oligosaccharide | 3-Indoleacetic acid |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Bioactive Compound Library | Selected Plant-Sourced Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Drug Repurposing Compound Library | Natural Product Library | Immunology/Inflammation Compound Library | Bitter Compound library | Bioactive Compounds Library Max | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Ancient Chinese Classical Formulas Compound Library | Food as Medicine Compound Library |
United States
