Choline chloride NEW

Choline chloride Cas 67-48-1

Specification

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Choline chloride is an organic compound and is the chloride salt form of choline. It is primarily used as an additive to provide choline, an essential nutrient, in animal feed and human dietary supplements. It appears as a white, hygroscopic (water-absorbing) crystalline solid and is highly soluble in water.

1. Its Role as an Essential Nutrient

Choline itself is often grouped with the B-complex vitamins due to its similar functions. It is a vital nutrient that the body cannot produce in sufficient amounts, making dietary intake necessary.

Choline chloride serves as a source of choline, which is critical for several bodily functions:

• Cell Membrane Integrity: Choline is a key component of phosphatidylcholine, a major phospholipid that makes up the structural framework of all cell membranes.

  Liver Health: It helps prevent a condition called non-alcoholic fatty liver disease by promoting the export of fat from the liver. Choline is necessary for packaging fats into lipoproteins so they can be transported through the bloodstream.

  Brain Function and Memory: Choline is a precursor to acetylcholine, a crucial neurotransmitter involved in muscle control, memory, mood, and other brain and nervous system functions.

  Gene Expression and Development: It is involved in methylation processes, which are essential for DNA synthesis and regulating gene expression. It is critically important during fetal development for healthy brain growth.

2. Primary Uses

A) Animal Feed (The Largest Application)
This is the most significant use of choline chloride, accounting for the majority of its global production. It is added to the feed of poultry (chickens, turkeys), swine, cattle, and aquaculture species.

• Purpose: Prevents choline deficiency, which can cause issues like perosis (slipped tendon disease) in poultry, reduced growth rates, and fatty liver syndrome. It ensures optimal growth, health, and productivity in livestock.

B) Human Dietary Supplements
Choline chloride is a common and cost-effective form of choline found in multivitamins, B-complex supplements, and standalone choline supplements.

• Purpose: Helps individuals meet their daily choline requirements, supporting liver, brain, and nerve health. It is particularly important for pregnant women for fetal brain development.

C) Industrial Applications

• Herbicide: It is used as a herbicide (as a salt of glyphosate) in some agricultural formulations.

  Oil Industry: It serves as a clay stabilizer in shale oil and gas extraction.

  Other Uses: It can be used in metalworking fluids and as a catalyst in certain chemical reactions.

3. Dietary Sources and Deficiency

While choline chloride is a supplemental source, choline is naturally present in foods like:

• Egg yolks

  Liver and other organ meats

  Soybeans

  Cruciferous vegetables (broccoli, cauliflower)

  Fish

Deficiency, though rare in healthy individuals eating a balanced diet, can lead to muscle damage, liver dysfunction (fatty liver), and potential neurological impairments.

Summary

In essence, choline chloride is the workhorse form of the essential nutrient choline. Its primary importance lies in its widespread use as a feed additive to support global livestock production and as a dietary supplement to ensure adequate choline intake for human health, particularly for liver function, brain development, and cellular structure.

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Contact information

Spring Zhang

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