Factory Provide Berberis Aristata Extract Berberine Hcl 633-65-8 98% Berberine Hydrochloride
Introduction
Product Name : Berberis Aristata Extract Berberine Hydrochloride Berberine Hcl
Other name: BERBERINE HCL;BERBERINE HYDROCHLORIDE;BERBERIN HCL;BERBERINE HYDROCHLORIDE N-HYDRATE
CAS No.:633-65-8
MF:C20H18ClNO4
MW:371.81
Melting Point :204-206 °C (dec.)
Appearance: Yellow powder
Storage :Sealed in dry,Sealed in dry,Room Temperature
Berberine Hydrochloride is an alkaloid derived from goldthread, bark of cork tree and other plants. It can be also synthesized in artificial method. It is used as raw material to make preparations, which are usually administered the treatment of intestinal infections and bacillary dysentery. Recently usage of anti-arrhythmic was found .Berberine Hydrochloride has effect on intestinal infections, bacillary dysentery.
| TECHNICAL DATE SHEET |
| PRODUCT SPECIFICATIONS |
| Product Name: | Berberis Aristata Extract |
| Botanic Name: | Berberis Aristata |
| Part of plant | Bark |
| Solvent extraction | waterðanol |
| Country of Origin: | China |
| Excipent | 10% maltodextrin |
| ANALYSIS ITEMS | SPECIFICATION | TEST METHOD |
| Appearance | Fine powder | Organoleptic |
| Color | Yellow fine powder | Visual |
| Odour & Taste | Characteristic | Organoleptic |
| Identification | Identical to R.S. sample | HPTLC |
| Berberine | 97% | Titration |
| Sieve Analysis | 100% through 80 mesh | USP39 <786> |
| Loss on drying | ≤ 5.0% | Eur.Ph.9.0 [2.5.12] |
| Total Ash | ≤ 5.0% | Eur.Ph.9.0 [2.4.16] |
| Lead (Pb) | ≤ 3.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Arsenic (As) | ≤ 1.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Cadmium(Cd) | ≤ 1.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Mercury(Hg) | ≤ 0.1 mg/kg -Reg.EC629/2008 | Eur.Ph.9.0<2.2.58>ICP-MS |
| Heavy metal | ≤ 10.0 mg/kg | Eur.Ph.9.0<2.4.8> |
| Solvents Residue | Conform Eur.ph. 9.0 <5,4 > and EC European Directive 2009/32 | Eur.Ph.9.0<2.4.24> |
| Pesticides Residues | Conform Regulations(EC) No.396/2005 including annexes and successive updates Reg.2008/839/CE | Gas Chromatography |
| Aerobic bacteria(TAMC) | ≤1000 cfu/g | USP39 <61> |
| Yeast/Moulds(TAMC) | ≤100 cfu/g | USP39 <61> |
| Escherichia coli: | Absent in 1g | USP39 <62> |
| Salmonella spp: | Absent in 25g | USP39 <62> |
| Staphylococcus aureus: | Absent in 1g |
|
| Listeria Monocytogenens | Absent in 25g |
|
| Aflatoxins B1 | ≤ 5 ppb -Reg.EC 1881/2006 | USP39 <62> |
| Aflatoxins ∑ B1, B2, G1, G2 | ≤ 10 ppb -Reg.EC 1881/2006 | USP39 <62> |
| Packing | Pack in paper-drums and two plastic-bags inside N.W. 25 kgs I.D.35xH51cm. |
| Storage | Store in a well-closed container away from moisture, light, oxygen. |
| Shelf Life | 24 months under the conditions above and in its original packaging |
Berberine HCL Benefits
1. Berberine Hydrochloride is used for damp-heat syndrome of the large intestine manifested as diarrhea, dysenteryand tenesmus.
2. Berberine Hydrochloride is used for acute febrile diseases with exces-sive pathogenic fire and heat manifested ashigh fever, dysphoria,unconsciousness anddelirium.
3. Berberine Hydrochloride is used for suppurative infections on the body surface, such as sores, carbuncles, furuncles and boils, septicemia induced by furuncu-losis, swellings and pain in the ears and eyes, canker sores in the mouth, exudative skin infections andpruritus.
Berberine HCL Mode of Action
1.Berberine hydrochloride has the function of removing heat and damp, relieving fire and eliminating toxins;
2. Berberine hydrochloride with the function of relaxing vascular smooth muscle and exciting other smooth muscle, such as bladder muscle, bronchial muscle and gastrointestinal muscel.
3. Berberine hydrochloride with the function of antimicrobial and antibacterial.Berberine hydrochloride primarily for the treatment of bacillary dysentery, pulmonary abscess, brucellosis, acute tonsillitis, maxillary sinusitis, oral and maxillofacial inflammation embolism.
China
