Amphotericin B CAS 1397-89-3 supplier in china
| Common Name | Amphotericin B |
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| CAS Number | 1397-89-3 | Molecular Weight | 924.079 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 1140.4±65.0 °C at 760 mmHg |
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| Molecular Formula | C47H73NO17 | Melting Point | >170°C |
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| Flash Point | 643.5±34.3 °C |
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| Exact Mass | 923.487854 |
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| PSA | 319.61000 |
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| LogP | 1.16 |
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| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
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| Index of Refraction | 1.614 |
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| Stability | Stable, but may be light sensitive. Incompatible with strong oxidizing agents. |
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| Water Solubility | sterile water: 20 mg/mL as a stock solution. Stock solutions should be stored at ?20 oC. Stable at 37oC for 3 days. | <0.1 g/100 mL at 21 oC |
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Amphotericin B is an antifungal medication used for serious fungal infections and leishmaniasis. The fungal infections it is used to treat include aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, and cryptococcosis. For certain infections it is given with flucytosine.
Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.
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