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S-Adenosyl-L-methionine disulfate tosylate, commonly abbreviated as SAMe (pronounced "Sammy"), is a synthetic form of a compound that naturally occurs in all living cells. It is formed from adenosine triphosphate (ATP) and methionine by the enzyme methionine adenosyltransferase. SAMe plays a crucial role in various biological processes, including the methylation of DNA, proteins, and lipids, as well as in the synthesis and metabolism of neurotransmitters.
The "disulfate tosylate" part of its name refers to its chemical formulation designed to stabilize the SAMe molecule, making it more suitable for use as a dietary supplement or pharmaceutical ingredient. This stabilization is necessary because SAMe is inherently unstable and can rapidly degrade when exposed to air or moisture.
SAMe has been extensively studied for its potential therapeutic effects and is available as an over-the-counter dietary supplement in some countries. It's most commonly used for:
1.Mood Enhancement: Research suggests that SAMe can act similarly to antidepressants by affecting serotonin metabolism. It may increase levels of serotonin and dopamine metabolites in the brain, which could help improve mood disorders such as depression.
2.Joint Health: Some studies indicate that SAMe has anti-inflammatory properties and may stimulate cartilage growth, making it beneficial for individuals suffering from osteoarthritis.
3.Liver Function: SAMe may also support liver health by contributing to glutathione production—a vital antioxidant that helps protect liver cells from damage—and by promoting detoxification processes.
Storage Condition: Dry, dark, and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years)
China
