Package : 500g/bag , 1kg/bag, 2kg/bag, 10kg/drum or customized
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Test Standard
USP42-NF37
ITEMS
CRITERIA
Appearance
White or almost white, amorphous or crystalline powder. Freely soluble in water and in propylene glycol.
Identification
IR
Same absorption bands as USP Hydroxypropyl Betadex RS
Clarity of Solution
Positive
Molar Substitution
0.40~1.50
Betadex
≤1.5%
Propylene Glycol
≤2.5%
Any Other Single Impurity
≤0.25%
Total Impurities Excluding Betadex and Propylene Glycol
≤1.0%
Propylene Oxide
≤1ppm
Loss on Drying
≤10.0%
Clarity of Solution
1.0g/2ml water solution is clear and transparent
Conductivity
≤200µS/cm
Bacterial Endotoxins Test
According to preparation needs
The total aerobic microbial count
≤1000cfu/g
The total combined moulds and yeasts count
≤100cfu/g
Packaging and storage
Preserve in well-closed containers. Store at room temperature.
Applications:
Hydroxypropyl-beta-cyclodextrin is one of the most widely used cyclodextrin derivatives in current scientific researches and industry applications. It mainly used in food, pharmaceutical and cosmetics industries.
1. In pharmaceuticals industry, hydroxypropyl-beta-cyclodextrin can increase solubility and bioavailability of insoluble drugs, so that the efficacy of drugs can last longer with less ingestion of drugs. It can adjust and control drugs release ratio, decrease side effects of drugs, and enhance stability of drugs. hydroxypropyl-beta-cyclodextrin can be used for oral medication, injection, mucosal delivery systems (including the nasal mucosa, rectum, cornea, etc.), dermal drug delivery systems, lipophilic drugs targeting delivery, and also used as protective agent and stabilizer of protein.
2. In food and perfume industry, hydroxypropyl-beta-cyclodextrin can enhance the stability of nutritional constituent and extend active time of effective constituent. It can cover up bad smell and bad taste of nutritional constituent. It also can improve production processes and product quality.
3. In cosmetics industry, hydroxypropyl-beta-cyclodextrin can reduce stimulate of organic molecular in cosmetic to the skin and mucosa. It can enhance the stability of matter, by preventing oxidation and volatilization of nutrients.
Shandong Binzhou Zhiyuan Biotechnology Co., LTD is a innovative enterprise that is professional in cyclodextrins and their applications. Supported by Shandong University, Zhiyuan Bio-tech has a cyclodextrins research center that located in Jinan.
We have a strong research and development strength of the technical team which hasclose cooperation with Shandong University, Chinese Academy of Science and other world class research institutes. Now we can produce hydroxypropyl cyclodextrin, sulfobutyl ether-beta-cyclodextrin sodium salt, methyl cyclodextrin, mercapto cyclodextrin, amino cyclodextrin, ethanediamine cyclodextrin, piroxicam cyclodextrin, cyclodextrin polymers and other cyclodextrin derivtives. We can also synthesis custom designed cyclodextrin derivatives for your requirements.
Now we have Ion chromatograph (IC), Capillary electrophoresis (CE), High performance liquid chromatograph (HPLC), Gas chromatograph (GC), Fourier transform infrared spectroscopy (FTIR) and other imported advanced testing equipments. Multiple means of analysis and inspection help us ensure production quality and accelerate new production developing.
We are proud of our R&D team that are formed by domestic and overseas experts in the field of cyclodextrin. We can provide first-class products and services for the partners in pharmaceutics, food, cosmetics, pesticides and new materials industries.
Sincerely willing to cooperate with you in future!
China
