Betaxolol hydrochloride

Product Name:

Betaxolol hydrochloride

Synonyms:

betoptic;kerlone;sl75212-10;sl-d.212;1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]propan-2-ol hydrochloride;Betaxolo;2-Propanol, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-, hydrochloride;Betoptima

CAS:

MF:

C18H30ClNO3

MW:

343.89

EINECS:

264-384-3

Product Categories:

Cardiovascular;Adrenoceptor

Mol File:

63659-19-8.mol

 

Betaxolol hydrochloride Chemical Properties

Melting point 

116°

storage temp. 

Store at RT

solubility 

H₂O: 36 mg/mL, soluble

form 

solid

color 

white

Merck 

14,1182

CAS DataBase Reference

63659-19-8(CAS DataBase Reference)

 

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

WGK Germany 

3

RTECS 

UA9823000

HS Code 

2922504500

Toxicity

LD50 in mice (mg/kg): 944 orally; 37 i.v. (Manoury)

MSDS Information

 

Betaxolol hydrochloride Usage And Synthesis

Description

Betaxolol hydrochloride is a cardioselective β-adrenergic blocker, reportedly devoid of intrinsic sympathomimetic and membrane stabilizing properties. Its long duration of action permits once-daily dosing in mild to moderate hypertension. It is also being evaluated in glaucoma.

Chemical Properties

White or almost white, crystalline powder.

Originator

Synthelabo (France)

Uses

antifungal

Definition

ChEBI: The hydrochloride salt of betaxolol.

Brand name

Betoptic (Alcon); Kerlone (Sanofi Aventis).

Biological Activity

Selective β 1 -adrenoceptor antagonist.