Irinotecan hydrochloride trihydrate

$ 2.00 /1kg

Min. Order1kg
Purity99%
Cas No136572-09-3
Supply Ability100kg
Update time2019-07-06

career henan chemical co

7YR

China

Chemical Properties

Product Name	Irinotecan hydrochloride trihydrate
CAS No	136572-09-3
EC-No
Min. Order	1kg
Purity	99%
Supply Ability	100kg
Release date	2019/07/06

Irinotecan hydrochloride trihydrate Basic information

Product Name:	Irinotecan hydrochloride trihydrate
Synonyms:	Irinotecan hydrochloride trihydrate, >=99%;Irinotecan HCL 3H2O;rinotecan hydrochloride trihydrate;(1,4’-bipiperidine)-1’-carboxylicacid,4,11-diethyl-3,4,12,14-tetrahydro-4-hyd;roxy-3,14-dioxo-1h-pyrano(3’,4’:6,7)indolizino(1,2-b)quinolin-9-ylester,mono;trihydrate,(s)-hydrochlorid;IRINOTECAN HYDROCHLORIDE TRIHYDRATE;IRINOTECAN MONOHYDROCHLORIDE TRIHYDRATE
CAS:	136572-09-3
MF:	C33H45ClN4O9
MW:	677.18
EINECS:	1308068-626-2
Product Categories:	Inhibitors;Anticancer;API;Anti-cancer&immunity
Mol File:	136572-09-3.mol

Irinotecan hydrochloride trihydrate Chemical Properties

Melting point	250-256°C (dec.)
Boiling point	257°C(lit.)
Merck	14,5091
CAS DataBase Reference	136572-09-3(CAS DataBase Reference)

Safety Information

Risk Statements	22
Safety Statements	20/21-22
RTECS	DW1060750

MSDS Information

Irinotecan hydrochloride trihydrate Usage And Synthesis

Chemical Properties	White powder
Uses	A DNA topoisomerase inhibitor.
Definition	ChEBI: A hydrate that is the trihydrate form of irinotecan hydrochloride. Onivyde is used in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active.
Brand name	Camptosar (Pharmacia &Upjohn) .
Hazard	Moderately toxic by ingestion.

Irinotecan hydrochloride trihydrate Preparation Products And Raw materials

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