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Irinotecan hydrochloride trihydrate

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Irinotecan hydrochloride trihydrate Basic information
Irinotecan hydrochloride trihydrate Chemical Properties
Safety Information
  • Risk Statements 22
  • Safety Statements 20/21-22
  • RTECS DW1060750
  • HS Code 29349990
Irinotecan hydrochloride trihydrate Usage And Synthesis
  • Chemical PropertiesWhite powder
  • UsesA DNA topoisomerase inhibitor.
  • DefinitionChEBI: A hydrate that is the trihydrate form of irinotecan hydrochloride. Onivyde is used in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active.
  • brand nameCamptosar (Pharmacia &Upjohn) .
  • HazardModerately toxic by ingestion.
Irinotecan hydrochloride trihydrate(136572-09-3)Related Product Information
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