Methotrexate

Product Name:

Methotrexate

Synonyms:

(S)-2-(4-(((2,4-DiaMinopteridin-6-yl)Methyl)(Methyl)aMino)benzaMido)pentanedioic acid;Methotrexate ;N-[4-[[(2,4-DiaMino-6-pteridinyl)Methyl]MethylaMino]benzoyl]-;Methoxtrexate;Trexall;(S)-2-(4-(((2,4-DiaMinopteridin-6-yl)Methyl)-(Methyl)aMino)benzaMido)pentanedioic acid, 95+%;Methotrexate solution ;BROMOCRESCOL PURPLE NA SALT HIGH PURITY

CAS:

MF:

C20H22N8O5

MW:

454.44

EINECS:

200-413-8

Product Categories:

Inhibitor;API;Anti-cancer&immunity;Inhibitors;Aromatic Esters;Antibiotics for Research and Experimental Use;Antitumors for Research and Experimental Use;Biochemistry;Others (Antibiotics for Research and Experimental Use);Intermediates & Fine Chemicals;Pharmaceuticals;API's;Antitumour;Aromatics;Bases & Related Reagents;Chiral Reagents;Heterocycles;Nucleotides

Mol File:

59-05-2.mol

 

Methotrexate Chemical Properties

Melting point 

195°C

Boiling point 

561.26°C (rough estimate)

density 

1.4080 (rough estimate)

refractive index 

1.6910 (estimate)

Fp 

11℃

storage temp. 

−20°C

solubility 

H₂O: insoluble

form 

powder

pka

pKa 3.04/4.99(H2O,t =25,I=0.0025) (Uncertain)

Water Solubility 

Insoluble. <0.1 g/100 mL at 19 ºC

Sensitive 

Light Sensitive & Hygroscopic

Merck 

14,5985

Stability:

Stable, but light sensitive and hygroscopic. Incompatible with strong acids, strong oxidizing agents. Store at -15C or below.

InChIKey

FBOZXECLQNJBKD-ZDUSSCGKSA-N

CAS DataBase Reference

59-05-2(CAS DataBase Reference)

NIST Chemistry Reference

Methotrexate(59-05-2)

EPA Substance Registry System

L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl) methyl]methylamino]benzoyl]- (59-05-2)