1. Product information
| Product Name: | Methotrexate |
| Synonyms: | METHOTREXATEFORINJECTION;sodium 4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]am ino]-5-hydroxy-5-oxo-pentanoate;METHOTREXATE(N-(4-(((2,4-DIAMINO-6-PTERIDINYL)METHYLAMINO)BENZOYL)-L-GLUTAMICACID);4-Amino-N10-methylfolic acid;Glutamic acid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, L-(+)- (8CI);L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- (9CI);L-Methotrexate;Methotrexat-Ebewe |
| CAS: | 59-05-2 |
| MF: | C20H22N8O5 |
| MW: | 454.45 |
| EINECS: | 200-413-8 |
| Product Categories: | Inhibitor;Anti-cancer&immunity;Aromatics;Bases & Related Reagents;Chiral Reagents;API;Aromatic Esters;Antibiotics for Research and Experimental Use;Antitumors for Research and Experimental Use;Biochemistry;API's;Antitumour;Heterocycles;Nucleotides;Others (Antibiotics for Research and Experimental Use);Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitors;59-05-2 |
| Mol File: | 59-05-2.mol |
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| Methotrexate Chemical Properties |
| Melting point | 195°C |
| Boiling point | 561.26°C (rough estimate) |
| alpha | +17～+24°(D/20℃)(c=1,Na2CO3 soln.)(calculated on the dehydrous basis) |
| density | 1.4080 (rough estimate) |
| refractive index | 1.6910 (estimate) |
| Fp | 11℃ |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | H2O: insoluble |
| form | powder |
| pka | pKa 3.04/4.99(H2O,t =25,I=0.0025) (Uncertain) |
| Water Solubility | Insoluble. <0.1 g/100 mL at 19 ºC |
| Sensitive | Light Sensitive & Hygroscopic |
| Merck | 14,5985 |
| BRN | 70669 |
| BCS Class | 3 |
| Stability: | Stable, but light sensitive and hygroscopic. Incompatible with strong acids, strong oxidizing agents. Store at -15C or below. |
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping
4. Contact information
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