USP Artemether Raw Powder CAS 71963-77-4 For Anti Malarial Factory Supply
Description
It is the derivative of artemisinin. This drug is a strong schizonticide and has rapid control of symptoms by destroying plasmodium. it is equally effective against chloroquine resistant strains of falciparum malaria.This drug is intended for the treatment of all kinds of malaria patients including the chloro-quine resistant falciparum malaria patients.
Name: Artemether
CAS No.: 71963-77-4
Molecular Formula: C16H26O5
Molecular Weight: 298.3746
Appearance: White powder
Melting Point: 86-89°C
Assay: 99%
Package: 25kg/drum
Artemether, isolated from Chinese-Vietnamese plant Artemisia annua L., locally called "qing hao", is used to treat fever and malaria. It is a white crystalline powder with a bitter taste; Practically insoluble in water, soluble in chloroform, acetone, and alcohols. Its chemical designation is (+)-(3-alpha, 5A-beta, 6-beta, 8A-beta, 9-alpha, 12-beta, 12aR)- decahydro- 10-methoxy- 3, 6, 9-trimethyl- 3, 12-epoxy- 12H-pyrano (4, 3-j)-1, 2-benzodioxepin.
Malaria is one of leading re-emerging infectious disease due to murative malarial parasite developed resistance to chloroquine. Sulfadoxine-pyrimethamine is an alternative can be used in the treatment of the disease resistant to chloroquine, but resistance to sulfadoxine- pyrimethamine has been reported also in some areas. Artemisinin is an alternative used in areas where the disease has become highly resistant to sulfadoxine-pyrimethamine. Dihydroartemisinin, its methyl ether (artemether), its ethyl ether (arteether) and its hemisuccinate ester (artesunate) are known as more effective than its parent material - artemisinin. But their activity decreases after one or two hours. For simultaneous administration to counter the drawback, combination therapy of artemisinin along with lumefantrine, mefloquine, amodiaquine, sulfadoxine, and pyrimethamine is useful. The term of artemotil refers to the pure beta-epimer of arteether. Artemisinin is a peroxide-bridged sesquiterpene lactone compound which has no N atom, unlike quinine class anti-malarial drugs. The characteristic peroxide lactone structure is indispensable for anti-malarial activity. This structure is also under the research for the treatment of cancer.
Function:
-Artemether is an alternative used in areas where the disease has become highly resistant to sulfadoxine-pyrimethamine.
-Artemether is used to treat fever and malaria.
-Artemether will be able to control symptoms, chloroquine against falciparum malaria with the same result. For various malaria treatment.
-Artemether can also be used for acute upper respiratory tract infection of patients with high fever, fever role stability.
Application:
1. Artesunate is an antimalarial agent. It is a water-soluble hemisuccinate derivative of dihydroartemisinin.
2. Artemisinin is a sesquiterpene lactone isolated from Artemisia annua, a herb that has traditionally been used in China for the treatment of malaria.
3. Artesunate and its active metabolite dihydroartemisinin are potent blood schizonticides, active against the ring stage of the parasite.
4. Artesunate is ideal for the treatment of severe malaria, including cerebral malaria. It is also active against chloroquine and mefloquine resistant strains of P. Falciparum.
5. Artesunate is unstable in neutral solution and is therefore only available for injections as artesunic acid.
Packaging details:
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Packaging details:
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25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.
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Storage:
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Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat
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Shelf Life:
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5 years if sealed and store away from direct sun light.
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Advantages:
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
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USP Artemether Raw Powder CAS 71963-77-4 For Anti Malarial Factory Supply
China
