4-(Trifluoromethoxy)aniline is used in the synthesis of anticancer agents and antitumor medicaments. Also, its an intermediate in the production of labelled Riluzole, a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant.
| Name | 4-(Trifluoromethoxy)aniline | EINECS | 207-317-5 |
| CAS No. | 461-82-5 | Density | 1.34 g/cm3 |
| PSA | 35.25000 | LogP | 2.74860 |
| Solubility | N/A | Melting Point | N/A
|
| Formula | C7H6F3NO | Boiling Point | 192.4 °C at 760 mmHg |
| Molecular Weight | 177.126 | Flash Point | 80.6 °C |
| Transport Information | UN 2941 6.1/PG 3 | Appearance | Clear yellow liquid |
Appearance and properties: This product is colorless liquid, b.p.73 ~ 75℃/1.34kpa, n20D 1.4630, relative density 1.3010, insoluble in water, soluble in benzene, toluene.
Density: 1.32g /mL at 20 °C(lit.)
Boiling point: 73-75 °C10 mm Hg(lit.)
Flash point: 177 °F
Refractive index: n20/D 1.463(lit.)
Stability: Stable under normal temperatures and pressures.
Storage conditions: Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container.
Vapor pressure: 2.97mmHg at 25°C
Usage:
1, 4-trifluoromethoxy-aniline is the intermediate of insecticide to kill zurea.
2, for the synthesis of fluorine-containing medicine, pesticide intermediates, etc
China
