Aciclovir Quick Detail
Alias: 2-amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-3H-purin-6-one
CAS: 59277-89-3
EINECS: 261-685-1
MF: C8H11N5O3
MW: 225.2
MP: 256-257°C
Appearance: White crystalline powders
Aciclovir
Description
Aciclovir (ACV), also known as acyclovir, is an antiviral medication. It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. Other uses include prevention of cytomegalovirus infections following transplant and severe complications of Epstein-Barr virus infection. It can be taken by mouth or injected.
Aciclovir is used for the treatment of herpes simplex virus and varicella zoster virus infections, including:
• Genital herpes simplex (treatment and prevention)
• Neonatal herpes simplex
• Herpes simplex labialis (cold sores)
• Shingles
• Acute chickenpox in immunocompromised patients
• Herpes simplex encephalitis
• Acute mucocutaneous HSV infections in immunocompromised patients
Bioavailability -15–20% (by mouth)
Protein binding - 9–33%
Biological half-life - 2–4 hours Excretion- Kidney (62–90% as unchanged drug)
Advantages:
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