1. Materials information
Names
| Name | 3,4-Diaminopyridine |
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| Synonym | More Synonyms |
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3,4-Diaminopyridine Biological Activity
| Description | Amifampridine is a drug, predominantly in the treatment of a number of rare muscle diseases.Target: OthersAmifampridine is a drug, predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is increased. Ca2+ channels can then be open for a longer time and allow greater acetylcholine release to stimulate muscle at the end plate. A 2005 systematic review from the Cochrane Collaboration found some data favouring its use in LEMS. Amifampridine is also used to treat many of the congenital myasthenic syndromes, particularly those with defects in choline acetyltransferase, downstream kinase 7, and those where any kind of defect causes "fast channel" behaviour of the acetylcholine receptor. From Wikipedia. |
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| Related Catalog | Signaling Pathways >> Others >> Others Research Areas >> Others |
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| References | [1]. http://en.wikipedia.org/wiki/3,4-Diaminopyridine#cite_note-4 |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 369.3±22.0 °C at 760 mmHg |
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| Melting Point | 216-218 °C(lit.) |
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| Molecular Formula | C5H7N3 |
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| Molecular Weight | 109.129 |
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| Flash Point | 204.9±9.5 °C |
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| Exact Mass | 109.063995 |
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| PSA | 64.93000 |
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| LogP | -0.09 |
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| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
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| Index of Refraction | 1.676 |
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| Water Solubility | 24 g/L (20 ºC) |
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2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
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