| CAS: | 598-78-7 |
| MF: | C3H5ClO2 |
| MW: | 108.52 |
| EINECS: | 209-952-3 |
| Product Categories: | API Intermediate;C1 to C5;Organic acids;Carbonyl Compounds;Carboxylic Acids |
| Mol File: | 598-78-7.mol |
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| 2-Chloropropionic acid Chemical Properties |
| Melting point | -12--14 °C |
| Boiling point | 170-190 °C(lit.) |
| density | 1.182 g/mL at 25 °C(lit.) |
| vapor pressure | 4 mm Hg ( 20 °C) |
| refractive index | n20/D 1.4345(lit.) |
| Fp | 215 °F |
| storage temp. | Store below +30°C. |
| solubility | H2O: soluble |
| pka | 2.96±0.10(Predicted) |
| form | clear liquid |
| color | Colorless to Almost colorless |
| PH | <1 (200g/l, H2O, 20℃) |
| Water Solubility | freely soluble |
| BRN | 1720259 |
| Exposure limits | ACGIH: TWA 0.1 ppm (Skin) |
| Stability: | Stable. Incompatible with strong oxidizing agents, strong bases. |
| LogP | 0.82 at 20.5℃ |
| CAS DataBase Reference | 598-78-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Propanoic acid, 2-chloro-(598-78-7) |
| EPA Substance Registry System | 2-Chloropropionic acid (598-78-7) |
| 2-Chloropropionic acid Usage And Synthesis |
| Description | 2-Chloropropionic acid is a colorless to white crystalline solid or liquid that is denser than water; therefore, can sink and mix with water. It has a slight odor and is the simplest chiral chlorocarboxylic aid. |
| Preparation | 2-Chloropropionic acid is prepared from diazotization of L-alanine in hydrochloric acid. |
| Application | 2-Chloropropionic acid is employed in the production of propargyl 2-chloropropionate (PCP), which is an atom transfer radical polymerization (ATRP) initiator, by the esterification of propargyl alcohol.
The chemical is also used in the synthesis of benzimidazole derivatives when treated with o-phenylenediamine phosphate.
It can also be used in the preparation of biologically active chitin derivative (1-carboxyethyl) chitosan.
It is used as a building block for the preparation of herbicides, dyestuffs, pesticides, as well as forestand agro-chemicals. |
| Biochemical Action | 2-Chloropropionic acid induces necrosis of granule cell layer of rat cerebellum when administered orally. |
| Safety | 2-Chloropropionic acid is a neurotoxin, as such it should be handled with utmost care. When inhaled, the chemical can irritate the nose, throat, and lungs, causing wheezing and coughing.
The chemical is a corrosive substance, which may occur by ingestion. Contact of the chemical with the eyes and skin may cause pain, irritation, redness, and severe burns. |
| Chemical Properties | colourless liquid |
| Uses | Intermediate for weed killers. |
| Uses | 2-Chloropropionic acid is used in the preparation of propargyl 2-chloropropionate (PCP), an atom transfer radical polymerization (ATRP) initiator, by the esterification of propargyl alcohol. It can be employed in the synthesis of a biologically active chitin derivative, (1-carboxyethyl) chitosan. It can be treated with o-phenylenediamine phosphate to synthesize benzimidazole derivatives.
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Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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