Chinese synonyms: Clenbuterol hydrochloride standard solution; Clenbuterol hydrochloride control substance; Clenbuterol hydrochloride/clenbuterol hydrochloride; Clenbuterol hydrochloride standard; Chloro - chloro - chloro - asthma; Clenbuterol hydrochloride; Dichlorolamine hydrochloride; Clenbuterol hydrochloride raw material English name: Clenbuterolhydrochloride English synonyms: NAB365CL; 4 - amino - alpha - ((tert - butylamino) methyl) - 3, 5 - dichlorobenzylalcoholhydrochlor; 4 - amino - alpha - ((tert - butylamino) mChemicalbookethyl) - 3, 5 - dichloro - benzylalcohomonohydr; 4 - amino - alpha - ((tert - butylamino) methyl) - 3, 5 - dichlorobenzylalkohol - hydrochlor; clenbuterolclorhidrato; nab365; leanmeatpowder; Molecular formula: planiparthydrochlorideCAS no. : 21898-19-1 C12H19Cl3N2O molecular weight: 313.65 EINECS no. : 244-643-7
Use and synthetic methods Properties clenbuterol hydrochloride is a white or almost white crystalline powder. Odorless, slightly bitter. It is soluble in water or ethanol, slightly soluble in chloroform or acetone, insoluble in ether. The chemical structure of clenbuterol hydrochloride is similar to adrenergic drugs, belonging to adrenergic drugs. It is a 2-receptor agonist, and has a high selective excitatory effect on bronchial, uterine and vascular smooth muscle 2-receptors, which can effectively relieve bronchospasm. In addition, there are strong anti-allergy and significantly enhance the activity of bronchial cilia, and used for lysosomes, can promote mucus dissolution, conducive to sputum discharge. Clinical type is mainly used for bronchial asthma and wheezing bronchitis, strong and durable, is the main drugs to prevent bronchial asthma and bronchial spasms, because this drug use less (20 ~ 40 g) dosage, drug and the prominent effect is fast, to maintain a long time, so this medicine contains the pharmacopoeia of the People's Republic of China in 2000, the second department. Its mechanism of action has been clarified. Selective adrenalin β2 receptor agonist clenbuterolhydrochloride (clenbuterolhydrochloride), a white crystalline powder in appearance, chemically named oxymethadine adrenaline or 2-[(tert-butamino-methyl] -4-amino-3, 5-dichlorobenzyl alcohol hydrochloride, The name of the drug is dichlorophenol amine, shu Chuan ning, Chemicalbook, etc. It is a powerful selective adrenalin β2 receptor agonist that can relax bronchial smooth muscle and is used in the treatment of bronchial asthma, asthmatic bronchitis and bronchitis with emphysema. Clenbuterol is the main component of clenbuterol hydrochloride. Because it can promote protein synthesis in muscle, promote fat decomposition and reduce fat accumulation, it can increase relative lean meat of animals and improve animal quality. Therefore, clenbuterol is also called "growth promoter" and "nutrient redistribution agent". It was discovered to promote animal growth in the early 1960s and introduced to livestock production in the US in the 1970s, making it the most widely used beta-stimulant in the world. However, due to the substance has strong thermal stability and biochemical stability, after eating animals, can form accumulative residues in the viscera and tissues, people eat pork containing clenbuterol will occur poisoning symptoms. Therefore, the application of β -stimulant in animal husbandry was prohibited in many countries, and the detection method of clenbuterol hydrochloride in feed and β -stimulant residues were developed in many countries. Clenbuterol hydrochloride as feed additive was banned by Chinese government in 1997. Precautions: A few patients may have mild palpitations, hand fibrillation, dizziness and other adverse reactions, continue to take medicine generally can gradually disappear. Use with caution in patients with hyperthyroidism, tachycardia or hypertension. Preparation: pass tablet, aerosol, suppository, film agent, patch, etc.
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