New oral broad-spectrum antibiotics. The antibacterial spectrum is similar to that of sulfonamides, but it is more effective for a variety of gram-positive and negative bacteria. It is not suitable to be used as an antibacterial agent alone because bacteria are prone to develop drug resistance. The combination of trimethoprim and sulfanilamide can enhance the antibacterial effect several times to dozens of times. This product is mainly used as synergist of sulfonic drugs. It can also be used as veterinary medicine to treat septicemia caused by Escherichia coli, pullorum, typhoid, cholera, secondary bacterial infection of respiratory system, etc. It can also be used in the treatment of coccidiosis.
China
