Dexamethasone sodium phosphate

CAS Number: 55203-24-2

Molecular formula: C22H28FNa2O8P

Molecular mass: 516.4

EINECS number: 219-243-0

Mechanism

(1) Anti-inflammatory effect: It can reduce and prevent the tissue's response to inflammation, thereby reducing the performance of inflammation. It can inhibit the accumulation of inflammatory cells, including macrophages and leukocytes, at the site of inflammation, and inhibit phagocytosis, the release of lysosomes, and the synthesis and release of inflammatory chemical mediators.

(2) Immunosuppressive effects: including preventing or suppressing cell-mediated immune responses, delayed allergic reactions, reducing the number of T lymphocytes, monocytes, and eosinophils, and reducing the binding of immunoglobulins to cell surface receptors Ability, and inhibit the synthesis and release of interleukins, thereby reducing the transformation of T lymphocytes to lymphocytes, and reducing the expansion of the primary immune response. It can also reduce the passage of immune review substances through the basement membrane, and can reduce the concentration of complement components and immunoglobulins.