55203-24-2

An inducer of apoptosis and inhibitor of the sodium phosphate symporter

ChEBI: Dexamethasone sodium phosphate is an organic sodium salt which is the disodium salt of dexamethasone phosphate. It has a role as a glucocorticoid receptor agonist. It contains a dexamethasone phosphate(2-).

Decadron (Merck); Dexacen (Cent); Dexacort (UCB); Dexair (Pharmafair); Hexadrol (Organon); Maxidex (Alcon).

Preparation of dexamethasone sodium phosphate for injection. Synthesis: Using dexamethasone acetate epoxide as the starting material, steps include a ring-opening reaction (HF/DMF, -10°C), recrystallization (methanol), base-catalyzed hydrolysis (Na2CO3/me