Benzyl alcohol

Melting point -15°C

Boiling point 205°C

Density 1.045g/mLat25°C(lit.)

Vapor density 3.7 (vsair)

Vapor pressure 13.3mmHg(100°C)

Refractive index n20/D1.539Chemicalbook(lit.)FEMA2137|BENZYLALCOHOL Flash point 201°F

Storage conditions 2-8°C

Solubility H2O: 33mg/mL, clear, colorless

Form Liquid

Function and purpose:

Benzyl alcohol is used as a preservative for ointments, a drying agent for fibers, nylon filaments and plastic films, a stabilizer for polyvinyl chloride, a photographic developer, cellulose acetate, ink, paint, paint, epoxy paint, dye, casein, Solvents such as shellac and gelatin to prepare benzyl ester or ether intermediates. It is also used in the preparation of spices and flavoring agents (mostly benzyl alcohol esters of fatty acids) as additives in soaps, perfumes, cosmetics and other products. Because it has almost the same refractive index as quartz and wool fibers, it is used as a distinguishing agent for quartz and wool fibers. The hydroxyl group of benzyl alcohol used as a fixative and diluent in the perfume industry is very active. It can react with benzene to form diphenylmethane, react with acrylonitrile to form N-benzylacrylamide (Ritter reaction), and can also react with phosphorus and halide Hydrohalic acid reacts to produce benzyl halide Chemicalbook. Benzyl halide and benzyl alcohol are both benzyl (benzyl) reagents used to give benzyl protecting groups to carboxylic acid and alcohol hydroxyl groups. The benzyl protecting group is easily removed by hydrogenation. In addition, benzyl alcohol is easily oxidized to benzoic acid by a variety of oxidants. If oxidized with nitric acid, aldehydes or acids can be generated depending on the concentration and temperature. When injecting penicillin, in order to prevent the patient from feeling too strong, benzyl alcohol is often used for anesthesia, so that the pain will not be too strong, so benzyl alcohol is also called "painless water." However, a common side effect was quickly discovered clinically: gluteal muscle contracture. This is because benzyl alcohol is not easily absorbed by the human body. Long-term accumulation at the injection site can cause necrosis of the surrounding muscles. In severe cases, it can even affect the development of bones. In 2005, the State Food and Drug Administration issued a document prohibiting the use of benzyl alcohol as a penicillin solvent injection.