English Name: (+) - griseofulvin
CAS No.: 126-07-8
Molecular formula: c17h17clo6
Molecular weight: 352.77
EINECS No.: 204-767-4
Melting point: 218-220 ° C(lit.)
Specific rotation: 354 º( c=1,dimethylform)
Boiling point: 469.04 ° C(roughestimate)
Form: Powder
Color: white to yellow white
Water solubility: practically in oluble
Indications:
Medically, this product is suitable for the treatment of all kinds of tinea, including tinea capitis, tinea mentagrophytes, tinea corporis, tinea cruris, tinea pedis and tinea onychomycosis. The above-mentioned tinea diseases are caused by deep red Trichophyton, Trichophyton interrupted, Trichophyton beard, Trichophyton interphalangeum, as well as Microsporum audouan, Microsporum canis, Microsporum gypsophilum and Epidermophyton flocculus. This product is not suitable for mild, limited superficial fungal infection and local use of antifungal drugs has been effective. Griseofulvin had no effect on Candida, Histoplasma, actinomycetes, Sporothrix, Blastomyces, coccobacterium, Nocardia, Cryptococcus and tinea versicolor. In agriculture, this product was first introduced by Brian et al. (1951) to control plant diseases. According to the existing research reports, it can control melon (Cucumis melo) Fusarium wilt, Fusarium wilt, anthracnose, apple flower rot, apple cold rot, apple tree rot, cucumber downy mildew, strawberry gray mold, gourd suspension blight, rose powdery mildew, chrysanthemum powdery mildew, lettuce flower rot, tomato early blight, tulip fire blight and other fungal diseases.
Application:
This product can inhibit all kinds of dermatophytes, including dermatophytes, dermatophytes and Microspora. It has no effect on tinea versicolor, Leuconostoc and bacterial chemicalbook. This product has bacteriostatic effect, and is effective for growing fungi. This product is used for tinea capitis, onychomycosis, tinea imbricata, tinea corporis and tinea corporis caused by sensitive fungi.
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