Product Name: Berberine hydrochloride
CAS: 633-65-8
MF: C20H18ClNO4
MW: 371.81
EINECS: 211-195-9
Melting point 204-206 °C (dec.)
storage temp. +2C to +8C
solubility methanol: soluble
form Yellow powder
Colour Index 75160
color Yellow powder
Uses
antiarrhythmic, alpha2 agonist, anticonvulsant, antiinflammatory, antibacterial, antifungal, antitrypanosomal, antineoplastic, immunostimulant
Uses
An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Al so inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation o f chemotherapeutic drugs.
Uses
An ingredient in some commercial eyewash products.