Product Name: Berberine hydrochloride
CAS: 633-65-8
MF: C20H18ClNO4
MW: 371.81
EINECS: 211-195-9
Melting point 204-206 °C (dec.)
storage temp. +2C to +8C
solubility methanol: soluble
form Yellow powder
Colour Index 75160
color Yellow powder
Chemical Properties yellow crystalline powder
Uses antiarrhythmic, alpha2 agonist, anticonvulsant, antiinflammatory, antibacterial, antifungal, antitrypanosomal, antineoplastic, immunostimulant
Uses An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Al so inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation o f chemotherapeutic drugs.
Uses An ingredient in some commercial eyewash products.