1. Materials information
| Name | β-propiolactone |
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| Synonym | More Synonyms |
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β-Propiolactone Biological Activity
| Description | Propiolactone (β-propiolactone; 2-Oxetanone) is a viral chemical inactivator that causes the infectious inactivation of viruses. Propiolactone was co-incubated with SARS-CoV at a ratio of 1:1000 (v:v) and used as a bacteriostatic agent to formulate the BPL-inactivated influenza virus vaccine (Flu-BPL)[1][2]. |
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| Related Catalog | Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV |
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| Target | SARS-CoV-2[1] |
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| References | [1]. Roberts A, et al. Immunogenicity and protective efficacy in mice and hamsters of a β-propiolactone inactivated whole virus SARS-CoV vaccine. Viral Immunol. 2010 Oct;23(5):509-19 [2]. Kulkarni R, et al. Anti-SARS-CoV-2 IgG antibody response among Indian COVID-19 patients using β-propiolactone-inactivated, whole virus-based indirect ELISA. J Virol Methods. 2021 Jan;287:113996. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 162.0±0.0 °C at 760 mmHg |
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| Melting Point | −33 °C(lit.) |
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| Molecular Formula | C3H4O2 |
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| Molecular Weight | 72.063 |
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| Flash Point | 35.0±16.1 °C |
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| Exact Mass | 72.021126 |
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| PSA | 26.30000 |
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| LogP | -1.33 |
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| Vapour Pressure | 2.2±0.3 mmHg at 25°C |
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| Index of Refraction | 1.445 |
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| Water Solubility | 37 g/100 mL |
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. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
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