Bromomethyl methyl ether is used as reagent for protection of OH groups as their methoxymethyl (MOM) ethers. It is used in enantiocontrolled synthesis of intermediate containing carbons 18 to 35 of the macrocyclic immunosuppressant FK-506. It was used in the synthesis of 1-methoxymethyl-4-tritylthio-2-azetidinone.
Bromomethyl Methyl Ether (BMME) is a lachrymator, possible carcinogen, handle with care. Extremely
destructive to tissue of mucous membranes, eyes, and skin. Wear respirator, chemical-resistant gloves, and
safety goggles.