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PIERICIDIN A

Basic information Safety Related Supplier
PIERICIDIN A Basic information
PIERICIDIN A Chemical Properties
  • Boiling point:614.9±55.0 °C(Predicted)
  • Density 1.044±0.06 g/cm3(Predicted)
  • Flash point:85 °C
  • storage temp. 2-8°C
  • pka5.21±0.33(Predicted)
  • form liquid
  • color green-yellow
Safety Information
MSDS
PIERICIDIN A Usage And Synthesis
  • UsesPiericidin A is the major analogue of a family of pyridyl antibiotics isolated from selected Streptomyces species. It is a specific, potent inhibitor of NADH-ubiquinone oxidoreductase (Complex I) that binds to ubiquinone binding site(s). Piericidin A inhibits both mitochondrial and bacterial NADH-ubiquinone oxidoreductases, binding close to NUOD-NUOB interface.
  • Enzyme inhibitorThis reduced antibiotic (FW = 423.64 g/mol; CAS 2738-64-9; Soluble in ethanol, methanol, DMF or DMSO) is a structural analogue of ubiquinone and a partially competitive inhibitor of bacterial and mitochondrial Type-I NADH-ubiquinone oxidoreductases (or Complex I). Octahydropiericidin A also inhibits glucose dehydrogenase.
PIERICIDIN A(2738-64-9)Related Product Information
PIERICIDIN ASupplierMore
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