Basic information Safety Related Supplier
ChemicalBook >  Product Catalog >  API >  Antiparasitic drugs >  Antiparasitic drugs >  Monensin

Monensin

Basic information Safety Related Supplier
Monensin Basic information
Monensin Chemical Properties
  • Melting point:103-105°C
  • alpha D +47.7°
  • Boiling point:608.24°C (rough estimate)
  • Density 1.0773 (rough estimate)
  • refractive index 1.5465 (estimate)
  • storage temp. 2-8°C
  • pka6.6 (in 66% DMF)
  • CAS DataBase Reference17090-79-8(CAS DataBase Reference)
  • EPA Substance Registry SystemMonensin (17090-79-8)
Safety Information
  • Hazard Codes T
  • Risk Statements 25
  • Safety Statements 36/37/39-45
  • RIDADR UN 3462 6.1/PG 2
  • WGK Germany 3
  • RTECS JH2830000
  • HazardClass 6.1(a)
  • PackingGroup II
  • Hazardous Substances Data17090-79-8(Hazardous Substances Data)
  • ToxicityLD50 of monensin complex in mice, chicks (mg/kg): 43.8 ± 5.2, 284 ± 47 orally (Haney, Hoehn)
MSDS
Monensin Usage And Synthesis
  • Chemical PropertiesCrystallin Solid
  • UsesMonensin A is a polyether antibiotic first isolated from Streptomyces cinnamonensis in 1967. Monensin A is a broad-spectrum anticoccicidial antibiotic, also exhibiting antifungal and antiviral activity. Monensin A forms complexes with monovalent cations such as Li+, Na+, K+, Rb+, Ag+ and Tl+ and is thus able to transport these cations across lipid membranes of cells, playing an important role as an Na+/H+ antiporter. It blocks intracellular protein transport and is used in animals to prevent coccidiosis, promote growth and prevent bloat. Derivatives of monensin, monensin methyl ester and particularly monensin decyl ester, are used in ion selective electrodes.
  • UsesMonensin A is a polyether antibiotic first isolated from Streptomyces cinnamonensis in 1967. Monensin A is a broad-spectrum anticoccicidal antibiotic, also exhibiting antifungal and antiviral activity. Monensin A forms complexes with monovalent cations such as Li+, Na+, K+, Rb+, Ag+ and Tl+ and is thus able to transport these cations across lipid membranes of cells, playing an important role as an Na+/H+ antiporter. It blocks intracellular protein transport and is used in animals to prevent coccidiosis, promote growth and prevent bloat. Derivatives of monensin, monensin methyl ester and particularly monensin decyl ester, are used in ion selective electrodes.
  • UsesPoliether antibiotic. Coccidiostat
  • brand nameCoban [as sodium salt] (Lilly);Rumensin [as sodium salt] (Lilly).
  • Safety ProfilePoison by ingestion and intraperitoneal routes. An eye and skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Monensin(17090-79-8)Related Product Information
MonensinSupplierMore
  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
  • Tel:18930552037 821-50328103-801
  • Email:3bsc@sina.com
  •  
  • Company Name:BEST-REAGENT
  • Tel:18981987031 400-1166-196
  • Email:cdhxsj@163.com;1955352637@qq.com;cdhxsj@163.com
  •  
  • Company Name:Jinan Haohua Industry Co., Ltd
  • Tel:0531-58773082
  • Email:sales@jnhaohua.com
  •  
  • Company Name:BOC Sciences
  • Tel:
  • Email:info@bocsci.com
  •  
  • Company Name:Shanghai LiuShi Pharmaceutical Technology Co., Ltd.
  • Tel:021-60135539
  • Email:shlschemical@hotmail.com
  •