(D)2-Rh 110 (trifluoroacetate salt)

(D)2-Rh 110 is a fluorogenic caspase substrate.1 Upon enzymatic cleavage by caspases, rhodamine 110 (Item No. 19061) is released in an apoptosis-dependent manner and its fluorescence can be used to quantify caspase activity. Rhodamine 110 displays excitation/emission maxima of 496/520 nm, respectively.WARNING This product is not for human or veterinary use.

[1] HUBERT HUG. Rhodamine 110-Linked Amino Acids and Peptides as Substrates To Measure Caspase Activity upon Apoptosis Induction in Intact Cells†[J]. Biochemistry Biochemistry, 1999, 38 42: 13906-13911. DOI: 10.1021/bi9913395